Our publications (2010-2014)
- G. Lingua, A. Copetta, D. Musso, S. Aimo, A. Ranzenigo, A. Buico, V. Gianotti, D. Osella, G. Berta,
Effect of arbuscular mycorrhizal and bacterial inocula on nitrate concentration in mesocosms simulating a wastewater treatment system relying on phytodepuration,
Environ. Sci. Pollut. Res., 2015, 22, 18616-18625.
doi: 10.1007/s11356-015-5502-7
- E. Gabano, M. Ravera, S. Tinello, D.
Osella,
Synthesis of Pt(IV)-biomolecule conjugates via click chemistry,
Eur. J. Inorg. Chem., 2015, 5335-5341.
doi: 10.1002/ejic.201501066
- M. Ravera, E. Perin, E. Gabano, I.
Zanellato, G. Panzarasa, K. Sparnacci, M. Laus, D. Osella,
Functional fluorescent nonporous silica nanoparticles as carriers
for Pt(IV) anticancer prodrugs,
J. Inorg. Biochem., 2015, 151, 132-142.
doi: 10.1016/j.jinorgbio.2015.08.001
- E. Gabano, S. Gama, F. Mendes, F.
Fregonese, A. Paulo, M. Ravera,,
Application of microwave-assisted heating to the synthesis of Pt(II)
complexes,
Inorg. Chim. Acta, 2015, 437, 16-19.
doi: 10.1016/j.ica.2015.07.042
- M. Ravera, E. Gabano, I. Zanellato, I.
Bonarrigo, M. Alessio, F. Arnesano, A. Galliani, G. Natile, D.
Osella,
Cellular trafficking, accumulation and DNA platination of a series
of cisplatin-based dicarboxylato Pt(IV) prodrugs,
J. Inorg. Biochem., 2015, 150, 1-8.
doi: 10.1016/j.jinorgbio.2015.05.012
- M. Ravera, E. Gabano, S. Bianco, G.
Ermondi, G. Caron, M. Vallaro, G. Pelosi, I. Zanellato, I.
Bonarrigo, C. Cassino, D. Osella,
Host-guest inclusion systems of Pt(IV)-bis(benzoato) anticancer drug
candidates and cyclodextrins,
Inorg. Chim. Acta, 2015, 432, 115-127.
doi: 10.1016/j.ica.2015.03.039
- G. Pelosi, M. Ravera, E. Gabano, F.
Fregonese, D. Osella,
Unprecedented one-pot synthesis of an unsymmetrical cisplatin-based
Pt(IV)-acetamidato complex,
Chem. Commun., 2015, 51, 8051-8053.
doi: 10.1039/C5CC02477C
- M. Ravera, A. Sharmin, E. Rosenberg,
Electrochemical studies of Ru(II) diimine bioconjugates,
Inorg. Chim. Acta, 2015, 429, 87-92.
doi: 10.1016/j.ica.2015.02.005
- V. Gandin, C. Marzano, G. Pelosi, M.
Ravera, E. Gabano, D. Osella,
Trans, cis, cis-bis(benzoato)dichlorido(cyclohexane-1R,
2R-diamine)platinum(IV): a prodrug candidate for the
treatment of oxaliplatin-refractory colorectal cancer,
ChemMedChem, 2014, 9, 1299-1305.
doi: 10.1002/cmdc.201400061
- E. Gabano, M. Ravera, D. Osella,
Pros and cons of bifunctional platinum(IV) antitumor prodrugs: two
are (not always) better than one (Dalton Perspective),
Dalton Trans., 2014, 43, 9813-9820.
doi: 10.1039/C4DT00911H
- I. Zanellato, I. Bonarrigo, D. Colangelo,
E. Gabano, M. Ravera, M. Alessio, D. Osella,
Biological activity of a series of cisplatin-based aliphatic
bis(carboxylato) Pt(IV) prodrugs: how long the organic chain should
be?,
J. Inorg. Biochem., 2014, 140, 219-227.
doi: 10.1016/j.jinorgbio.2014.07.018
- M. Ravera, E. Gabano, G. Pelosi, F.
Fregonese, S. Tinello, D. Osella,
A New Entry to Asymmetric Platinum(IV) Complexes Via Oxidative
Chlorination,
Inorg. Chem., 2014, 53, 9326-9335.
doi: 10.1021/ic501446b
- G. Ermondi, G. Caron, M. Ravera, E. Gabano,
S. Bianco, J. A. Platts, D. Osella,
Molecular Interaction Fields vs. Quantum-Mechanical-based
descriptors in the modelling of lipophilicity of platinum(IV)
complexes,
Dalton Trans., 2013, 42, 3482-3489.
doi: 10.1039/C2DT32360E
- E. Petruzzella, N. Margiotta, M. Ravera, G.
Natile,
NMR investigation of the thermal- and/or photo-induced reduction of
trans dihydroxido Pt(IV) derivatives,
Inorg. Chem., 2013, 52, 2393-2403.
doi: 10.1021/ic302100x
- E. Gabano, S. Gama, F. Mendes, M. B.
Gariboldi, E. Monti, S. Bombard, S. Bianco, M. Ravera,
Study of the synthesis, antiproliferative properties, and
interaction with DNA and polynucleotides of cisplatin-like Pt(II)
complexes containing carcinogenic polyaromatic amines,
J. Biol. Inorg. Chem., 2013, 18, 791-801.
doi: 10.1007/s00775-013-1022-4
- M. Alessio, I. Zanellato, I. Bonarrigo, E.
Gabano, M. Ravera, D. Osella,
Antiproliferative activity of Pt(IV)-bis(carboxylato) conjugates on
malignant pleural mesothelioma cells,
J. Inorg. Biochem., 2013, 129, 52-57.
doi: 10.1016/j.jinorgbio.2013.09.003
- I. Zanellato, I. Bonarrigo, M. Ravera, E.
Gabano, R. Gust, D. Osella,
The hexacarbonyldicobalt derivative of aspirin acts as a
CO-releasing NSAID on malignant mesothelioma cells,
Metallomics, 2013, 5, 1604-1613.
doi: 10.1039/C3MT00117B
- M. Ravera, E. Gabano, I. Zanellato, I.
Bonarrigo, E. Escribano, V. Moreno, M. Font-Bardia, T. Calvet, D.
Osella,
Synthesis, characterization and antiproliferative activity on
mesothelioma cell lines of bis(carboxylato)platinum(IV) complexes
based on picoplatin,
Dalton. Trans., 2012, 41, 3313-3320.
doi: 10.1039/C2DT11874B
- L. Gaviglio, A. Gross, N. Metzler-Nolte, M.
Ravera,
Synthesis and in-vitro cytotoxicity of cis, cis, trans-diammine
dichlorido disuccinatoplatinum(IV)-peptide bioconjugates,
Metallomics, 2012, 4, 260-266.
doi: 10.1039/C2MT00171C
- M. Ravera, E. Gabano, M. Sardi, E. Monti,
M. B. Gariboldi, D. Osella,
Antiproliferative Activity of PtII Complexes with
Carboxylated Phosphanes in Chelated or Ring-Opened Forms,
Eur. J. Inorg. Chem., 2012, 3441-3448.
doi: 10.1002/ejic.20120028210
- N. Margiotta, C. Marzano, V. Gandin, D.
Osella, M. Ravera, E. Gabano, J. A. Platts, E. Petruzzella, J. D.
Hoeschele, G. Natile,
Revisiting [PtCl2(cis-1,4-DACH)]: An Underestimated Antitumor
Drug with Potential Application to the Treatment of
Oxaliplatin-Refractory Colorectal Cancer,
J. Med. Chem., 2012, 55, 7182-7192.
doi: 10.1021/jm3006838
- S. Gama, F. Mendes, T. Esteves, F. Marques,
A. Matos, J. Rino, J. Coimbra, M. Ravera, E. Gabano, I. Santos, A.
Paulo,
Synthesis and biological studies of pyrazolyl-diamine Pt(II)
complexes containing polyaromatic DNA-binding groups,
ChemBioChem, 2012, 13, 2352-2362.
doi: 10.1002/cbic.201200472
- I. Zanellato, I. Bonarrigo, E. Gabano, M.
Ravera, N. Margiotta, P. G. Betta, D. Osella,
Metallo-drugs in the Treatment of Malignant Pleural Mesothelioma,
Inorg. Chim. Acta, 2012, 393, 64-74.
doi: 10.1016/j.ica.2012.06.005
- J. A. Platts, M. Ravera, E. Gabano, M.
Sardi, S. Bianco, D. Osella,
Solvolysis of a Series of Cisplatin-like cis/[PtCl2(en*)]
(en* = variously N-Methylated Ethylenediamines) Complexes.
Comparison between DNA-biosensor and Conductivity Data,
Eur. J. Inorg. Chem., 2012, 5625-5631.
doi: 10.1002/ejic.201200677
- M. Ravera, E. Gabano, M. Sardi, G. Ermondi,
G. Caron, M. J. McGlinchey, H. Müller-Bunz, E. Monti, M. B.
Gariboldi, D. Osella,
Synthesis, characterization, structure, molecular modeling studies
and biological activity of sterically crowded Pt(II) complexes
containing bis(imidazole) ligands,
J. Inorg. Biochem., 2011, 105, 282-291.
doi: 10.1016/j.jinorgbio.2010.12.002
- G. Caron, M. Ravera, G. Ermondi,
Molecular Interaction Fields (MIFs) to predict lipophilicity and
ADME-Tox profile of antitumor Pt(II) complexes,
Pharm. Res., 2011, 28, 640-646.
doi: 10.1007/s11095-010-0317-1
- J. A. Platts, G. Ermondi, G. Caron, M.
Ravera, E. Gabano, L. Gaviglio, G. Pelosi, D. Osella,
Molecular and statistical modeling of reduction peak potential and
lipophilicity of platinum(IV) complexes,
J. Biol. Inorg. Chem., 2011, 16, 361-372.
doi: 10.1007/s00775-010-0731-1
- M. Ravera, E. Gabano, M. Sardi, M. Alessio,
D. Osella,
Electrochemical biosensor assay of the interaction between [PtCln
(NH3)4-n](2-n) (n = 0-4) complexes
and ds-DNA,
Eur. J. Inorg. Chem., 2011, 1635-1639.
doi: 10.1002/ejic.201001338
- C. Francisco, S. Gama, F. Mendes, F.
Marques, I. C. dos Santos, A. Paulo, I. Santos, J. Coimbra, E.
Gabano, M. Ravera,
Pt(II) complexes with bidentate and tridentate pyrazolyl-containing
chelators: synthesis, structural characterization and biological
studies,
Dalton. Trans., 2011, 40, 5781-5792.
doi: 10.1039/C0DT01785J
- M. Gál, J. Híveš, M. Laus, K. Sparnacci, M.
Ravera, E. Gabano, D. Osella,
Electrostatic Interaction of Negatively-Charged Core Shell
Nanoparticles with Antitumoral Cationic Platinum-Based Complexes,
Eur. J. Inorg. Chem., 2011, 3289-3294.
doi: 10.1002/ejic.201100454
- E. Moreno, E. Gabano, E. Torres, J. A.
Platts, M. Ravera, I. Aldana, A. Monge, S. Pérez-Silanes,
Studies on Log Po/w of Quinoxaline di-N-Oxides: A
Comparison of RP-HPLC Experimental and Predictive Approaches,
Molecules, 2011, 16, 7893-7908.
doi: 10.3390/molecules16097893
- I. Zanellato, I. Bonarrigo, M. Sardi, M.
Alessio, E. Gabano, M. Ravera, D. Osella,
Evaluation of Pt-Ethacrynic Conjugates in the Treatment of
Mesothelioma,
ChemMedChem, 2011, 6, 2287-2293.
doi: 10.1002/cmdc.201100426
- N. Margiotta, R. Ostuni, S. Piccinonna, G.
Natile, I. Zanellato, C. D. Boidi, I. Bonarrigo, D. Osella,
Platinum-bisphosphonate complexes have proven to be inactive
chemotherapeutics targeted for malignant mesothelioma because of
inappropriate hydrolysis,
J. Inorg. Biochem., 2010, 105, 548-557.
doi: 10.1016/j.jinorgbio.2010.12.011
- M. Ravera, D. Musso, F. Gosetti, C.
Cassino, E. Gamalero, D. Osella,
Oxidative degradation of 1, 5-naphthalenedisulfonic acid in aqueous
solutions by UV-photolysis in the absence and presence of H2O2,
Chemosphere, 2010, 79, 144-148.
doi: 10.1016/j.chemosphere.2010.01.022
- S. Bombard, M. B. Gariboldi, E. Monti, E.
Gabano, L. Gaviglio, M. Ravera, D. Osella,
Biological activity of enantiomeric complexes [PtCl2L2]
(L2 is aromatic bisphosphanes and aromatic diamines),
J. Biol. Inorg. Chem., 2010, 15, 841-850.
doi: 10.1007/s00775-010-0648-8
- P. Gramatica, E. Papa, M. Luini, E. Monti,
M. B. Gariboldi, M. Ravera, E. Gabano, L. Gaviglio, D. Osella,
Antiproliferative Pt(IV) complexes: synthesis, biological activity,
and quantitative structure-activity relationship modeling,
J. Biol. Inorg. Chem., 2010, 15, 1157-1169.
doi: 10.1007/s00775-010-0676-4